What is the best way to set up a simple website with a database?

I have a personal website and it will have a page where people can submit a kind of message to me. I need to be able to store these messages and access them from anywhere on the site. Currently my site is very simple with just HTML5 and CSS3. I will of course be adding JavaScript as is necessary. I want to add in a way to store and retrieve these "messages". What is the best way to do this?